New team member: Dr. Marco Castro
On March 1, 2019, Dr. Marco Castro joined the Angiogenesis & Metabolism Laboratory. Marco earned his Ph.D. in 2018 in the famous laboratory of Prof. Dr. Christer Betsholtz at Uppsala University, Sweden. His Ph.D. thesis focused on the role of the small-GTPase CDC42 in endothelial cells during blood vessel morphogenesis in the central nervous system and its implications in cerebral vasculopathies. Marco now aims to expand his skills and investigate the molecules and pathways that drive organ-specific specialization of blood vessels.
If you want to read about Marco’s exciting research, please click here:
CDC42 Deletion Elicits Cerebral Vascular Malformations via Increased MEKK3-Dependent KLF4 Expression. Castro M, Laviña B , Ando K, Álvarez-Aznar A, Abu Taha A, Brakebusch C, Dejana E, Betsholtz C, and Gaengel K. Circulation Research 2019
Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations. Laviña B, Castro M, Niaudet C, Cruys B, Álvarez-Aznar A, Carmeliet P, Bentley K, Brakebusch C, Betsholtz C, Gaengel K. Development 2018